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A novel membrane anchor for FtsZ is linked to cell wall hydrolysis in Caulobacter crescentus.

Meier EL1, Razavi S2, Inoue T2,3, Goley ED1. Abstract In most bacteria, the tubulin-like GTPase FtsZ forms an annulus at midcell (the Z-ring) which recruits the division machinery and regulates cell wall remodeling. Although both activities require membrane attachment of FtsZ, few membrane anchors have been characterized. FtsA is considered to be the primary membrane[…]

Asymmetric Damage Segregation Constitutes an Emergent Population-Level Stress Reseponse

Highlights Lineages and growth rate distributions reveal effects of ADS Asymmetry of segregation is dependent on single-cell damage The population benefit of ADS increases with stress Summary Asymmetric damage segregation (ADS) is a mechanism for increasing population fitness through non-random, asymmetric partitioning of damaged macromolecules at cell division. ADS has been reported across multiple organisms,[…]